Dermatology Online

Urticaria



Recommended Diagnostic Tests In frequent urticaria subtypes

Types Subtypes Routine diagnostic tests Additional diagnostic tests

Spontaneous Urticaria Acute spontaneous urticaria None None
Chronic spontaneous urticaria Differential blood count, ESR and/or CRP Autologous serum skin test, test for *Helicobacter pylori*, gastroscopy, ANA, D-dimer, stool examination for parasites, skin test including physical test, specific IgE, thyroid hormone, and autoantibodies

Inducible Urticaria Cold urticaria Cold provocation and threshold test: Melting ice cube on the volar forearm/Temp Test (4 °C) for 5 minutes Differential blood count, ESR or CRP, rule out other diseases, especially infections
Delayed pressure urticaria Pressure test and threshold test: Vertical pressure (stimulates wheal reaction within 3-12 hours) None
Heat urticaria Heat provocation and threshold test: Heat source/Temp Test (45 °C) for 5 minutes None
Solar urticaria Expose patient to ultraviolet and multi-wavelength visible light and threshold test Rule out other light-induced dermatoses
Symptomatic dermographism Elicit dermographism and threshold test: Moderate stroking of the skin with a blunt object
Vibratory urticaria/angioedema Test with vibration, for example, apply vortex vibration to forearm or fingers for 1-5 minutes None
Aquagenic urticaria Provocation testing: Apply wet room temperature clothing to forearm for 15-20 minutes
Cholinergic urticaria Provocation and threshold testing, for example, by exercise or hot bath for 15-20 minutes** None
Contact urticaria Immunologic and non-immunologic reactions can be the cause. Diagnostic tests include patch test and skin prick testing. Dermatologic or/and specialist consultations are recommended.

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